Mounjaro and other GLP-1 weight loss medications can cause a number of common side effects, such as diarrhoea.
Some patients will experience this side effect when starting their treatment, and will find it fades usually after a few days. As you progress through the dosages, you may also find you experience this side effect when you increase your dosage for the first time as well.
Whilst uncomfortable, there are a number of things that you can do to reduce and manage the symptoms being experienced:
Drink plenty of water
Ensuring you keep your fluid levels up avoids any risk of dehydration, which can in turn make these symptoms worse as well as having other effects on our body.
If you are unable to keep water down, please speak with your GP or call NHS 111 for an urgent same-day appointment
Try over the counter treatments
There are over the counter medications that will help manage the symptoms of diarrhoea and help your body recover:
Dioralyte sachets - oral rehydration sachets
Loperamide capsules - slows down the movement of the gut and bowels
Need further support?
If the above methods are not helping you manage your side effect, our clinical team is on hand to give further support and advice as needed - just complete this form and they will be in touch Monday to Friday.
Should you find that your symptoms are worsening or if they are stopping you from doing your day-to-day tasks, please ensure to speak with your GP or NHS 111 for an urgent appointment.
Please ensure to call 999 or go to A&E (if you are able) if you notice a sharp/severe pain in the upper abdomen (stomach): https://www.nhs.uk/conditions/acute-pancreatitis/
Although this is an uncommon side effect, Pancreatitis is a severe condition which can get worse very quickly and can be life-threatening.
Last reviewed - 14/01/2025